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To figure out if JHN has a risk for hepatotoxicity and needs N-acetylcysteine treatment, we will use the Rumack-Matthew nomogram
This form is highly regarded for its improved bioavailability and effectiveness in supporting detoxification, immune health, and antioxidant defenses
A report from Japan indicated that homologous expression of codon-optimized MT-ND3 in patients with MT-ND3 mutations can increase ATP production and improve mitochondrial function, showing promise as a potential new treatment strategy (71)
& Sarkadi, B
SURF1 deficiency: a multi-Centre natural history study
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