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However, plasma levels of SHBG are approximately two times higher in women than in men, because E2 increases the hepatic synthesis of this globulin

[1] [2] As of the time of writing, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA), and is not commercially available in the UK through licensed channels

PMCID: PMC9556320

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