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Out of necessity, the researchers in this study used medical record documentation of opioid poisoning and alcohol intoxication as proxies for opioid and alcohol use
Putting the numbers in context Here is a side-by-side comparison of peak weight loss results from both compounds
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
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