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Cerebral extracellular chemistry and outcome following traumatic brain injury: a microdialysis study of 223 patients

Clinical trials on semaglutide (the GLP-1 sold as Wegovy and Ozempic, for example) and tirzepatide (sold as Zepbound and Mounjaro) estimate that within a few years of starting treatment, people may experience a loss of muscle mass equal to 20 years of age-related decline

and that any discrepancies from the study as planned (and, if relevant, registered) have been explained

Source: Busines NewsWire

Stimulant laxatives such as bisacodyl (Dulcolax) or senna (Senokot) are appropriate for intermittent or adjunct use