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What stood out: CagriSema achieved 23.0% weight loss at 84 weeks (efficacy estimand) Tirzepatide achieved 25.5% On the treatment-regimen estimand, weight loss was 20.2% vs 23.6% Primary endpoint not met: CagriSema did not demonstrate non-inferiority vs tirzepatide on weight loss at 84 weeks Why this matters This is a reminder that in obesity pharmacotherapy, very effective and best-in-class are not the same conversation
Third, protecting the function of aging-related tissues and organs
Contains folic acid and magnesium, which are critical for neurotransmitter synthesis
But does it directly influence our weight
Most patients get them weekly or biweekly, depending on their treatment plan
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