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It prevents the formation of advanced glycation end products (AGEs), which contribute to age-related diseases, such as diabetes, cardiovascular disease, and neurodegenerative disorders (Nagai et al., 2012)
This obstruction can lead to urine retention within the kidney, increased renal pelvis pressure, tubular dilation, cellular phenotypic transformation, apoptosis, glomerular damage, and interstitial inflammation
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In addition, dimorphic fungi such as Benjaminiella poitrasii , Mucor racemosus , and Schizophyllum commune have been reported to possess different NAD + - and NADPH-glutamate dehydrogenase activities when growing in the yeast and filamentous forms 14,15,16
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