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Because Glp1r mRNA is also expressed in the human OB 53 , it is intriguing to explore in future studies whether intranasal administration of GLP-1 agonists 54 could potentially exert their effects by acting in the OB (a site of persistent sensitivity to GLP-1 in obesity according to our data)
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Dipeptidyl peptidase-4 inhibitor MK-626 restores insulin secretion through enhancing autophagy in high fat diet-induced mice
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