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87 An additional metabolite generated through the Kyn pathway is the essential redox cofactor nicotinamide adenine dinucleotide (NAD+), a molecule of fundamental importance for the maintenance of cellular homeostasis

The risk of MACE was also significantly reduced in consecutive studies (Harmony Outcomes [18], REWIND [19], AMPLITUDE-O [20])

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A sharp drop in appetite may unintentionally reduce protein, fiber, and overall nutrient intake