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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

Morris D et al

In a comprehensive 2015 review published in BioMed Research International , Pickart and colleagues integrated three decades of preclinical and clinical research on GHK-Cu, reporting that the molecule stimulates collagen, elastin, glycosaminoglycan, and decorin synthesis in human dermal fibroblasts

Together, these data demonstrate that the observed changes in mitochondrial abundance caused by 5FU are mediated through its inhibitory action on TS