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The correlation between inflammation and GLP-1 level is complicated: it was shown that endogen GLP-1 is elevated in inflammatory settings, such as critically ill patients or after cardiac surgery
Phase 2 trial data shows that nausea occurred in 14% of participants at the 1mg dose but jumped to 45% at the 12mg dose
These observations suggest that omnivorous individuals represent an appropriate study population for investigating interventions to reduce TMAO production
Gough SCL, Bode BW, Woo VC, Rodbard HW, Linjawi S, Zacho M, et al
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