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CD4 is thought to have arisen relatively recently in teleost fish following duplication of a two Ig domain-containing ancestral gene, CD4REC (Laing et al., 2B) (Laing et al., 2A shows only mammals

Belli M, Barone L, Bellia A, et al

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Moreover, G3 presented a significant increase ( p = 0.015, p = 0.006, p = 0.036, p = 0.045) in SOD, GPx, CAT and TAC (439.5 u/g, 85.11 u/g, 38.96 nmol/g, and 141.2 nmol/g) respectively