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For the narrower MACE-3 composite of cardiovascular death, myocardial infarction, or stroke, 27 events occurred among participants receiving retatrutide compared with 23 in the placebo group, resulting in a hazard ratio of 1.12 (95% CI: 0.64-1.96)
These variants not only determine disease susceptibility but also reshape tissue-specific epigenomic landscapes (Ling et al., 2022)
pubmed.ncbi.nlm.nih.gov/41476424 U.S
