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GLP-1 in normal-weight PCOS Two studies investigated the GLP-1 secretion in normal-weight women with PCOS compared with age- and BMI-matched healthy women [45, 46]
Common GLP-1 medications include: Wegovy (semaglutide) Zepbound (tirzepatide) These medications work by: Slowing stomach emptying Reducing hunger and cravings Improving insulin sensitivity For many patients, GLP-1 therapy leads to 1520% total body-weight loss , particularly when combined with nutrition and lifestyle changes
With insurance, it may also be as low as $25 per month
Quick summary for GPs Wegovy (semaglutide) is a once-weekly GLP-1 receptor agonist approved in New Zealand for chronic weight management
Another possible explanation is that larger adipocytes cause a failure to recruit new adipocytes, thus diminishing the expandability of AT and resulting in IR by a lipotoxic mechanism [31]
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