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Our preliminary data suggest that GLP-1s suppress intake through a different mechanism, DiFeliceantonio said

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She adds another explanation for why some individuals might seem to observe this association: Weight gain is also linked to the perimenopausal and post-menopausal state, and a GLP-1 is a reasonable treatment for this for those who qualify. What this means is that for some women, the weight loss effects of a GLP-1 and the symptoms of low estrogen may occur at the same time, making it difficult to tell whether the changes are due to the medication, hormonal shifts, or both

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