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Over the past several decades, its prevalence has risen at an alarming rate worldwide, reaching pandemic proportions and showing no signs of stabilization [1, 2]

In another study, people who took semaglutide lost, on average, 3.6% of their body weight after 3 months, 5.8% after 6 months, and 8.3% after 12 months

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As an analog of endogenous amylin, it is studied for its receptor-mediated signaling dynamics, sustained activation profile, and downstream neuroendocrine cascades within controlled laboratory environments

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