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IL-4 and IL-13 suppress the production of filaggrin, a structural protein critical for maintaining the stratum corneum

Thus, this may be interpreted as the direct demonstration of the estrogen, GM, and bone metabolism connection ( In clinical settings, researchers investigated 106 PMW with normal bone mass, osteopenia, and OPusing a research method based on 16S rRNA gene sequencing and LC-MS metabolomics and found that the gut microbiome of patients with PM underwent significant alterations