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Citation: Maksimovich N.Ye., Bon E.I, (2024), Cell Antioxidant Systems, Clinical Trials and Clinical Research
Extracellular matrix components and inflammatory cytokine expression
It contains glutathione, one of the bodys most important natural antioxidants, along with hydrolyzed marine collagen (types I and III), vitamin C, L-cysteine, and coenzyme CoQ10 making it a complete formula that promotes radiance, clarity, and vitality in the appearance of the skin
Under basal conditions, NRF2 is kept inactive through binding to its negative regulator KEAP1, which is a redox-regulated substrate adaptor for the Cullin (Cul)3-RING-box protein (Rbx)1 ubiquitin ligase complex that directs NRF2 for degradation [10]
The effect is dose-dependent, most pronounced during titration, and typically improves within 12-16 weeks as the gut adapts to slower transit times
