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The short answer: Creatine isn't a fat burner, and it may actually cause a temporary uptick in scale weight at first

Optical density (OD) was measured at 570 nm using a BioTek Epoch 2 microplate reader (BioTek Instruments

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In recent years, the role of different acyl-CoAs in the posttranslational acylation of protein lysine residues has acquired increasing attention (42)

That is the strongest class of evidence there is for a side effect: measured in randomised, controlled approval trials