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Because retatrutide still lacks FDA approval, researchers continue to study its full safety profile

In studies, most nausea, diarrhea, and vomiting occurred when people increased their dose but the effects generally decreased over time

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The positive effects of growth hormone-releasing peptide-6 on weight gain and fat mass accrual depend on the insulin/glucose status

Participants were excluded if they had significant medical histories, abnormal lab results, or conditions affecting alcohol metabolism or absorption of the investigational product