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doi: 10.1080/03007995.2022.2081454 138 LemogneCGouraudCPitronVRanqueB

In vivo studies have shown that VEGF enhances vascularization and reduces retrograde degeneration of corticospinal tract axons and thus stimulates axon regeneration in the injured brain area (Conforti et al

Clinical trials using combinations of CoQ10 with cross-linked hyaluronic acid (XL-HA) have shown enhanced treatment outcomes in DED patients, attributed to CoQ10s antioxidant effects and HAs inherent water retention and viscoelasticity properties, which are essential for repairing ocular tissues (Postorino et al., 2018

STEP and SURMOUNT trials didnt standardize specific injection times, and post-hoc analyses found no differences in efficacy by time of day