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One of the most significantly upregulated pathways in cardiomyocytes from semaglutide-treated animals was BCAA catabolism: nearly every enzyme in this pathway was significantly upregulated, including the two enzymes required to initiate BCAA catabolism, Bcat2 and the BCKD subunits ( Figure 3C-D )

What Experts and Scientists Are Actually Saying Coverage of this topic has been heavy on political narrative and light on the underlying scientific debate