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When combining treatments, it is important to: Avoid doubling up on corticosteroids without clinical oversight combining high-dose inhaled steroids with oral prednisolone increases cumulative systemic steroid exposure and should only occur under clinician supervision Continue prescribed maintenance therapies (e.g., antihistamines, nasal sprays) even when taking prednisolone, unless advised otherwise Follow the prescribed dose and duration of prednisolone carefully, as stopping abruptly after prolonged use can cause adrenal insufficiency Your GP or allergy specialist will tailor the combination of treatments to your specific condition, severity, and medical history

That guidance may include: confirming whether the medication is appropriate in the first place reviewing contraindications and risk factors discussing expected side effects and red flags setting realistic dosing and escalation plans helping with hydration and protein intake identifying when exercise should be modified, not abandoned following outcomes beyond just pounds lost For some patients, that broader structure is best delivered through a Medical Weight Loss Program