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Side effects and safety GHK-Cu is very well-tolerated
La evidencia reciente motiv un cambio del enfoque teraputico glucocntrico al cardiorrenometablico con la inclusin en las reco mendaciones internacionales de nuevas terapias con beneficios cardiovasculares y renales Contribucin del artculo al conocimiento actual Se describen los efectos directos e indirectos de los agonistas del receptor del pptido similar al glucagn tipo 1 (GLP-1) segn los estudios clnicos y de la vida real, que confirman sus efectos beneficiosos sobre la funcin renal en diabetes e introducen la expectativa de los estudios en curso con objetivos renales
Across the trials, the absolute risk differences (ARD) between intervention and placebo groups were minimal, generally ranging from 0.9% to + 0.9%, indicating no consistent increase in risk with GLP-1 receptor agonists
Not recommended for use in individuals with asthma due to the possibility of increasing its symptoms
It is expected that early combination therapy modifies the natural history of the disease
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