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When she checked her genitals, anus and buttocks, Dr Rosas said the skin appeared to be charred and sunburnt

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Instead, the maintenance of an approximately constant wave velocity strongly supports the existence of a reaction-diffusion-like excitable system, in which oxidative stress in one region triggers de novo ROS amplification in adjacent cells, thereby enabling a self-propagating wave of ferroptotic contagion

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Immunoprecipitation was then performed using the Catch and Release Immunoprecipitation Kit (EMD Millipore), according to the manufacturers instructions with 250 g of total protein from cells or 400 g from tissues, and 1 g of an anti-IGF-1R antibody (#9750, Cell Signaling)