2020;19(6):e13124
Ushioda, R
All three medications help lower blood sugar, but they have also gained attention for benefits that extend beyond diabetes management alone Today , healthcare providers consider how these medications affect kidney health, heart health, and long-term complications (e.g., not just the effects these meds have on your glucose levels)
The beneficial effect of tirzepatide on hsCRP, a biomarker of systemic inflammation, YKL-40, a proinflammatory cytokine, and ICAM-1, a biomarker of endothelial dysfunction, was already detectable at 4 weeks, consistent with the salutary effects of GIP and GLP-1 on inflammation and atherosclerosis in experimental models [84,85,86]
This pattern repeats throughout treatment and is driven by fluid dynamics that scientists still do not fully understand