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The metabolism and clearance of both components may be affected by significant liver disease, and patients with severe hepatic impairment should be monitored closely if treatment is deemed necessary

All use is limited to in-vitro and preclinical research settings

Similarly, Toxoplasma gondii , an obligate intracellular protozoan, forms a parasitophorous vacuole (PV) within host cells, which closely associates with host mitochondria in a process termed host mitochondrial association (HMA) ( Toxoplasma gondii reduces parasite growth and virulence, underscoring the importance of mitochondrial hijacking for parasitic survival (Powell et al., 2024)

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