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NAA exerts its function in a histone acetyltransferase P300/CBP-associated factor (PCAF)-dependent manner, leading to lamin A acetylation, impairing its interaction with Sun2 (Sad1 and Unc84 domain-containing protein 2) and subsequent lytic granules, from CD8 + T cells and NK cells, polarization and release [214]
Pharmacological inhibition of CD45 phosphatase presents a promising therapeutic strategy
Misaligned feeding uncouples daily rhythms within brown adipose tissue and between peripheral clocks
Lopes-Ramos, C
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