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Reduction in major cardiovascular events (SELECT trial, semaglutide) Reduced risk of progressing from prediabetes to type 2 diabetes (Tirzepatide, 3yr trial) Weight reduction significantly improves sleep apnea severity confirmed in multiple GLP-1 trials Emerging ADA 2026 data on GLP-1 anti-inflammatory effects and osteoarthritis improvement Improved basal metabolic rate and energy utilisation, especially with tirzepatides GIP pathway We believe cost transparency is part of quality care
Marchetti F, Zacchini S, Zanotti V
Risk tolerance varies between individuals
Expert Interview Julie Brow-Polanco
Retatrutide skin sensitivity alone is rarely a reason to stop treatment
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