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Although it counteracted DEX-induced spatial memory deficits, the results observed with SERT in healthy mice corroborate the report of a study by Siepmann et al [81] that showed that in healthy humans, SERT was not associated with cognitive deficits or improvements in cognition
Their research included the pioneering mapping of histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a) and histone H3 symmetrically dimethylated at arginine 2 (H3R2me2s), which are the products of protein arginine methyltransferases (PRMT) 1 and 5, respectively