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In parallel, increased activity of lipid metabolic enzymes, including acyl-CoA synthetase long-chain family member 4 ( ACSL4 ) and lysophosphatidylcholine acyltransferase 3 ( LPCAT3 ), promotes the enrichment and remodeling of polyunsaturated fatty acids (PUFAs) in membrane phospholipids (Yang and Stockwell, 2016
Both are essential for reducing oxidative stress, the harmful condition caused by free radicals that contribute to cell and tissue damage
Following 1 year of treatment, DI improved by 94% in YOD along with improvement in HbA1c
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Most patients see best results with 1-3 weekly treatments over 4-8 weeks
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