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March 2022: More than four years after launch, Novo Nordisk finally adds gallbladder warnings to the labelunfortunately, too late for thousands of patients who already had their gallbladders removed

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Primary outcomes measured safety through AEs monitoring, anti-drug antibody development, immune cell biomarker changes via flow cytometry, T-cell proliferation assays, and cytokine production in peripheral blood mononuclear cells, while secondary outcomes included clinical response using MS and endoscopic assessment

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There were no significant correlations between metabolite component scores and antipsychotic dose in either patient group, nor were there significant correlations with age