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You should take it extra seriously if you: Take blood thinners (or high-dose aspirin) Use NSAIDs often (ibuprofen, naproxen) Had a peptic ulcer or past GI bleeding Have liver disease (risk of esophageal varices) Drink heavy alcohol often Are older, or you already have anemia Have new belly pain, vomiting, or sudden weakness Even if you feel okay, risk factors raise the chance that black stool is not just food or medicine

Kraemer WJ, Spiering BA, Volek JS, Ratamess NA, Sharman MJ, Rubin MR, et al

The results will be different for everyone

A 2021 study found that combining exercise with GLP-1 medication led to greater healthy weight loss than using either approach on its own

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