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Funding The National Natural Science Foundation of China (31960141), the Gansu Provincial Scientific Research Project on Traditional Chinese Medicine (GZKP-2021-21), the Gansu Provincial Science and Technology Programme (23JRRA1254), the Lanzhou Municipal Science and Technology Programme (2022-4-56), and the Lanzhou Municipal Science and Technology Development Programme (2018-1-122), and the Lanzhou Municipal Science and Technology Programme (2022-3-39)

Statistical analysis Statistical analyses were conducted using IBM SPSS Statistics software (version 26.0, IBM, Chicago, IL, USA) and GraphPad Prism (version 8.2.1, GraphPad Software, San Diego, CA, USA) for data visualization