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Less common side effects include acid reflux symptoms, injection site irritation, or changes in bowel habits

Months 12: Dose Escalation & Adjustment Semaglutide starts at a low dose (0.25 mg/week) and increases gradually over 1620 weeks to minimize nausea and GI side effects

The mechanism is plausible and well-described

Damage to nerve tissue (peripheral neuropathy), leading to pain, numbness, and weakness in extremities: These can be caused by the vitamins role in the proper functioning of the nervous system

These improvements occurred while many participants reduced or eliminated concurrent diabetes medications