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Clinical implication Although the association between GLP-1 RAs and gallbladder/biliary diseases has been supported by multiple studies, causality has not been definitively established

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Although recent reviews have described the role of GLP-1 RAs on cardiovascular risk in general, there is a lack of evidence synthesis on local actions of GLP-1 RAs in coronary arteries and the link of these mechanisms to coronary events ((Figure 1)