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This paper adds a 14th type of EDS to the EDS classification by delineating a novel EDS type caused by genetic defects in AEBP1, thereby expanding the list of EDS-associated genes to 20

At high glucose levels, glycolysis is dominant and glycolytic intermediates and products are utilized to generate ATP as well as lipids and amino acids

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It can also be integrated into aesthetic routines where the aim is to visibly improve melasma, uneven skin tone, dull skin, visible hyperpigmentation and signs of photoageing, as well as to reinforce the antioxidant action of other brightening and revitalising active ingredients