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Shatsky[23], who examined evidence derived from the use of oral and intramuscular administration, indicated that high dose oral administration appeared to be safe, effective and cost-effective, although long term clinical trials were required to confirm this
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The copper ion may dissociate from the GHK tripeptide, and free copper ions are pro-oxidant
The therapy had a variety of beneficial physiological effects, including the initiation of a rise in glutathione, which might have further contributed to the positive functional effects of the therapy
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