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Curr Atheroscler Rep 24(11):867884

Additionally, it has been suggested that GIPR agonists and antagonists might target different CNS receptor populations, with evidence showing that acylated peptide GIPR agonists act on GABAergic neurons to further reduce food intake and body weight when combined with GLP-1R agonists in mice 39,40

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However, the researchers found that intracellular lipoxygenase levels were significantly increased

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