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By attenuating inflammation and oxidative stress, curcumin improves insulin receptor signaling and enhances insulin sensitivitymechanisms that are particularly relevant given the shared inflammatory and insulin-resistant states underlying diabetes and depression (Sarmiento-Ortega et al., 2025)

An unopened vial has the longest possible window

Technically, yes, but a face wash may not be effective at breaking down oil-based makeup and can leave your skin feeling dry if it doesn't have makeup-dissolving properties

doi:10.1098/rsos.210382

"Glutathione as a skin whitening agent: Facts, myths, evidence and controversies." Indian J Dermatol Venereol Leprol