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Yes, whilst most patients experience weight loss on Ozempic, some individuals may gain weight due to compensatory eating patterns, reduced physical activity from gastrointestinal side effects, concurrent medications, or improved glycaemic control reducing glucose loss in urine
SEMA also reversed cerebral microcirculation effects of HFD by reducing capillary rarefaction and the interaction of leukocytes in postcapillary brain venules
doi: 10.1152/japplphysiol.00599.2016
3,094 non-diabetic, obese men ages 1850 who received a prescription of semaglutide were identified and subsequently matched to an equal number cohort of non-diabetic, obese men who never received a prescription of semaglutide
People who take phentermine and experience progress with weight loss may also need adjustments in the dosages of insulin or other diabetic medications to prevent low blood sugar
