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Understanding this interaction can open up new avenues for treatments aimed at preventing or modulating eryptosis to improve AKI management, with particular attention to CRRT techniques that may be applied in severe cases
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The coexistence of other thiol-containing biomolecules like cysteine (Cys) and homocysteine (Hcy) in plasma complicates the accurate and selective detection of GSH [89]
up to 10 mM in liver the most abundant non-protein thiol in mammalian cells Redox forms: Reduced GSH (active) and oxidised GSSG
Evaluates neuroprotection in laboratory injury models
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