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Growth factor signaling, particularly involving pathways linked to vascular endothelial growth factor (VEGF) and fibroblast activity, appears to promote cell migration, collagen formation, and tissue regeneration

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The formation of metal-flavonoid complexes significantly enhances their bioavailability, positioning these compounds as promising candidates for next-generation therapeutics ( Ehretia tinifolia extract (ETME) counteracts this response by activating the protective Nrf2/HO-1 pathway while suppressing NF-B/MAPK-mediated inflammation