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It is prescription-only, offered after clinical assessment against BMI-based eligibility, and used as an adjunct to a reduced-calorie diet and increased physical activity

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Gene ontology analysis was executed using clusterProfiler (version 3.18.0) and metascape( sgLuciferase/Ythdf2 PNT RNA-Seq analysis methods Differential gene expression analysis was performed on RNA-seq data

Due to their inhibitory effects on T cell activation and function, DPP-4 inhibitors (DPP-4i) have been successfully evaluated in vivo as immunosuppressive therapies using animal models of rheumatoid arthritis (RA), multiple sclerosis (MS), and transplantation

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