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That long duration is one of the underlying reasons semaglutide is weekly rather than daily
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Symptoms typically emerge during dose titration and often diminish over several weeks, though some individuals experience persistent gastrointestinal upset requiring dose adjustment or discontinuation
497 Current studies suggest administering 1.5 to 2 times the maintenance fluid volume within the first 24 h of admission, with close monitoring of urine output
MACEs, major adverse cardiac events
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