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In a recent RCT, ertugliflozin improved left ventricular global longitudinal strain in people with type 2 diabetes mellitus and pre-HF, effects associated with increased ACE2 and angiotensin (17) levels, suggesting a potential underlying mechanisms [91]
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Some practitioners use a twice-daily split (e.g., 250 mcg morning, 250 mcg post-workout) for injuries they consider higher grade
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