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Decrotonylation of MTHFD1 at the 354/553 sites enhances cellular resistance to ferroptosis and promotes cancer cell development (Zheng et al
Moreover, at moderate levels, ROS oxidatively modifies KEAP1, thereby activating the NRF2 pathway, which induces the transcription of antioxidant genes such as SOD2, GPX1, and HO-1, establishing a defense against oxidative stress in granulosa cells [236]
Why is Glutathione Considered The Best Antioxidant
[PubMed] Melkonian EA, Asuka E, Schury MP
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