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Week 8-10 (Post-protocol): Retest everything you ran at baseline
Use it twice a day for best results
A dominant-negative human Gs (DNGs) with 8 mutations (S54N, G226A, E268A, N271K, K274D, R280K, T284D and I285T) was generated by site-directed mutagenesis to limit G protein dissociation 47
Long term (weeks 812): Consistency completely dominates timing
It also makes the treatment easier for patients
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