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Despite lower efficacy and tolerability shown by nasally administered PYY agonists in early studies, long-acting subcutaneous PYY receptor agonists such as PYY 1875 are undergoing early-phase clinical trials to evaluate their safety and effectiveness as monotherapy or in combination with GLP-1 receptor agonists for the treatment of obesity
This anti-inflammatory profile has generated significant interest in conditions beyond metabolic disease
Accompanying the increase in use of these drugs has been a surge in individuals seeking guidance regarding their side effects, as well as accidental overdoses
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