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The final concentration of 25 M FOXO4-DRI was added to the cells in a DMEM containing 2% FBS or 10% FBS

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3.2 Antithyroid medications Although the European Thyroid Association recommends consideration of definitive therapy for all patients, some subgroups may benefit from any antithyroid drug therapy, including intolerant patients to thionamides, patients with a large goiter, and young patients who may undergo additional exposure to radiation or surgery during a lifetime [34]