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A paired Students t-test was used to compare kinetic parameters before and after DEM treatment

To determine whether the colistin-induced depolarization was the result of the opening of the mitochondrial permeability transition pore (mPTP), mitochondria were co-incubated with colistin and cyclosporin A, a well-characterized desensitizer of the mPTP 31,32

It can easily be misinterpreted without effective clinico-histological correlation, making a good working relationship between Clinician and Histopathologist essential for correct diagnosis

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Food & Drug Administration (FDA) would disagree with DSIPs designation as incredibly safe, as the peptide is included on its list of bulk drug substances with significant safety risks